Bovine Calf Serum (BCS)
$27.31 – $72.66
Laboratories across the world use Bovine Calf Serum (BCS) as a growth source for many cell types In vitro. BCS provides proper growth for human Embryo Fibroblast as well as models of hepatitis. PurMa Biologics collects Bovine Calf Serum (BCS) from calves less than 12 months old.
Description
Bovine Calf Serum (BCS)
Background
Laboratories around the globe use Bovine Calf Serum (BCS) to support the growth of many cell types In vitro. BCS provides proper growth for human Embryo Fibroblast as well as models of hepatitis. Moreover, it performs well with U937 macrophage , Human lymphocytes as well as blood cells including cord blood cells, T and B lymphocytes We collect Bovine Calf Serum (BCS) from calves less than 12 months old.
Bovine Calf Serum (BCS) Vs. Fetal Bovine Serums (FBS)
- BCS Contains approximately two folds protein compared to fetal bovine serum (FBS), among them, are Iggs and other antibodies.
- Contains less growth factors than fetal bovine serum, however, is proven to be adequate for the above-mentioned cell lines.
- Importantly, it is much more cost-effective than Fetal Bovine Serum (FBS).
Special Features
- PurMaTM Bovine Calf Serum (BCS) has US origin.
- PurMa TM Bovine Calf Serum (BCS) has been triple-filtered through 0.1 µM filters.
- PurMa Biologics sterilizes BCS with gamma irradiation methodology.
- PurMa Biologics performs heat-inactivation on our BCS .
- Has been tested for mycoplasma as well as endotoxin (see below), see the certificate of analysis.
- Has been tested on multiple cell lines, such as Hek293, COS1, and NS1 cells.
Analysis
For full Analysis performed on all PurMa Bovine and Horse Serums click here , as well as in ” Documents” Tab: Routine Pathological Analysis on PurMa Bovine and Horse Serums
References
- Mitogenicity of fetal calf serum. Gergely et al. 1977;11(3-4):259-63. PMID: 311308
- Fetal Calf Serum Exerts an Inhibitory Effect on Replication of Duck Hepatitis A Virus Genotype 1 in Duck Embryo Fibroblast Cells. Wang, et al. Viruses. 2020 Jan 9;12(1):80. doi: 10.3390/v12010080. PMID: 31936491.
- Eicosanoid Content in Fetal Calf Serum Accounts for Reproducibility Challenges in Cell Culture. Niederstaetter et al. 2021 Jan 15;11(1):113. doi: 10.3390/biom11010113. PMID: 33467719.
Methodology | Unit measured | Accepted level | Result |
Sterility (Current USP and EP 2.6.1 for Bacteria & Fungi) | NA | Not Detected | Not Detected |
pH | N/A | measured | 6.58 |
Osmolality (USP 785) mOsm/KgH2 | mOsm/KgH20 | 280-340 | 288 |
Hemoglobin (Fleming & Woolf) | mg/dL | <25 | 12.9 |
Endotoxin (USP 85) | EU/mL | <20 | <0.100 |
Mycoplasma (Barile & Kern; Large Volume, Direct Culture) | NA | Not Detected | Not Detected |
IgG | Elliza | Measured | 0.19 ug/ml |
Albumin | Eliza | Measured | ≤ 4.6 g/dL |
Virus Testing (9 CFR 113.53c) | |||
Bovine Adenovirus | NA | Not Detected | Not Detected |
Bovine Parvovirus | NA | Not Detected | Not Detected |
Bovine Respiratory Syncytial Virus | NA | Not Detected | Not Detected |
Bovine Viral Diarrhea Virus | NA | Not Detected | Not Detected |
Rabies | NA | Not Detected | Not Detected |
Reovirus | NA | Not Detected | Not Detected |
Cytopathogenic Agents (IBR) | NA | Not Detected | Not Detected |
Hemadsorbing Agents (PI3) | NA | Not Detected | Not Detected |
Bluetongue | NA | Not Detected | Not Detected |
Additional information
Size | 1 x 50 ml, 1 x 500 ml |
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Quality Control
[vc-quality-control-tab]SDS
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